S16/2 Protein phosphorylation site analysis on different hybrid linear ion trap mass spectrometers
نویسندگان
چکیده
منابع مشابه
Top-down protein sequencing and MS3 on a hybrid linear quadrupole ion trap-orbitrap mass spectrometer.
Top-down proteomics, the analysis of intact proteins (instead of first digesting them to peptides), has the potential to become a powerful tool for mass spectrometric protein characterization. Requirements for extremely high mass resolution, accuracy, and ability to efficiently fragment large ions have often limited top-down analyses to custom built FT-ICR mass analyzers. Here we explore the hy...
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Instruments that trap ions in a magnetic and/or electric field play a very important role in the analysis of biomolecules. The two predominant instruments in the category of trapping instrument are the quadrupole ion trap mass spectrometer (QIT-MS) and the ion cyclotron resonance (ICR) MS. The latter is also commonly called Fourier transform MS (FT-MS). The QIT is an inexpensive, simple, and ru...
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As a driver for many biological processes, phosphorylation remains an area of intense research interest. Advances in multiplexed quantitation utilizing isobaric tags (e.g., TMT and iTRAQ) have the potential to create a new paradigm in quantitative proteomics. New instrumentation and software are propelling these multiplexed workflows forward, which results in more accurate, sensitive, and repro...
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ژورنال
عنوان ژورنال: Biochimica et Biophysica Acta (BBA) - Bioenergetics
سال: 2008
ISSN: 0005-2728
DOI: 10.1016/j.bbabio.2008.05.417